About this calculator
Cockcroft-Gault creatinine clearance is commonly used in medication dosing references. The correct weight choice depends on the drug and protocol.
Uses Cockcroft-Gault creatinine clearance: ((140 − age) × weight kg) / (72 × serum creatinine), multiplied by 0.85 for the female equation.
Source-mapped educational formula
Cockcroft-Gault is an estimate and may be inaccurate in acute kidney injury, obesity, underweight, elderly frailty, pregnancy, amputations, dialysis, or rapidly changing creatinine.
Formula and method
CrCl = ((140 − age) × weight in kg) / (72 × Scr mg/dL), multiplied by 0.85 for the female equation.
Limitations and when not to rely on this result
- Cockcroft-Gault is an estimate and may be inaccurate in acute kidney injury, obesity, underweight, elderly frailty, pregnancy, amputations, dialysis, or rapidly changing creatinine.
- Medication dosing requires the drug label, local renal dosing guidance, body-weight policy, and clinician/pharmacist judgment.
- Do not use as the only basis for high-risk drug dosing decisions.
Frequently asked questions
Is Cockcroft-Gault the same as eGFR? +
No. Cockcroft-Gault estimates creatinine clearance in mL/min, while eGFR is usually indexed to 1.73 m².
Which weight should I use? +
Use the drug-specific protocol. Some medications use actual, ideal, or adjusted body weight.
Can this be used in acute kidney injury? +
It is unreliable when serum creatinine is changing rapidly.
Is this for children? +
No. Pediatric renal dosing requires pediatric methods.
Why does my lab not report Cockcroft-Gault? +
Many labs report CKD-EPI eGFR instead; Cockcroft-Gault remains common in drug dosing references.